Chirality's Role in Actin Filament Mechanics
Analysis
Key Takeaways
- •Introduces a coarse-grained model for simulating chiral actin filaments.
- •The model allows for the prediction and control of filament shape and mechanical properties.
- •Demonstrates the impact of chirality on motor-driven dynamics, including filament rotation and coiling.
- •Provides a framework for mesoscale simulations applicable to various helical filaments.
“The model predicts and controls the shape and mechanical properties of helical filaments, matching experimental values, and reveals the role of chirality in motor-driven dynamics.”