Computational Modeling for Pediatric PAH Progression
Analysis
Key Takeaways
- •Developed patient-specific cardiovascular models for pediatric PAH patients.
- •Used longitudinal MRI and catheterization data for model calibration.
- •Automated calibration process significantly reduced calibration time.
- •Model-derived metrics correlated with clinical indicators of disease severity.
- •Computational modeling offers a promising tool for monitoring and informing treatment strategies for pediatric PAH.
“Model-derived metrics such as arterial stiffness, pulse wave velocity, resistance, and compliance were found to align with clinical indicators of disease severity and progression.”