Model-Assisted Bayesian Estimators for Ordinal Outcomes in RCTs

This paper addresses the limitations of traditional methods (like proportional odds models) for analyzing ordinal outcomes in randomized controlled trials (RCTs). It proposes more transparent and interpretable summary measures (weighted geometric mean odds ratios, relative risks, and weighted mean risk differences) and develops efficient Bayesian estimators to calculate them. The use of Bayesian methods allows for covariate adjustment and marginalization, improving the accuracy and robustness of the analysis, especially when the proportional odds assumption is violated. The paper's focus on transparency and interpretability is crucial for clinical trials where understanding the impact of treatments is paramount.