AI Framework for CMIL Grading

This paper introduces INTERACT-CMIL, a multi-task deep learning framework for grading Conjunctival Melanocytic Intraepithelial Lesions (CMIL). The framework addresses the challenge of accurately grading CMIL, which is crucial for treatment and melanoma prediction, by jointly predicting five histopathological axes. The use of shared feature learning, combinatorial partial supervision, and an inter-dependence loss to enforce cross-task consistency is a key innovation. The paper's significance lies in its potential to improve the accuracy and consistency of CMIL diagnosis, offering a reproducible computational benchmark and a step towards standardized digital ocular pathology.